diff --git a/sqlmesh/core/engine_adapter/snowflake.py b/sqlmesh/core/engine_adapter/snowflake.py
index 37ca6eee22..758e4847c1 100644
--- a/sqlmesh/core/engine_adapter/snowflake.py
+++ b/sqlmesh/core/engine_adapter/snowflake.py
@@ -757,14 +757,32 @@ def close(self) -> t.Any:
     def get_table_last_modified_ts(self, table_names: t.List[TableName]) -> t.List[int]:
         from sqlmesh.utils.date import to_timestamp
 
-        num_tables = len(table_names)
-
-        query = "SELECT LAST_ALTERED FROM INFORMATION_SCHEMA.TABLES WHERE"
-        for i, table_name in enumerate(table_names):
+        # INFORMATION_SCHEMA only contains the objects of the database it belongs to, so the tables
+        # are grouped by database and each group is looked up in its own database's INFORMATION_SCHEMA.
+        # The groups are keyed on the catalog identifier rather than its name, because quoting matters
+        # in Snowflake: unquoted raw is the database RAW, while quoted "raw" is a different database
+        catalogs_to_tables: t.Dict[t.Optional[exp.Identifier], t.List[exp.Table]] = {}
+        for table_name in table_names:
             table = exp.to_table(table_name)
-            query += f"""(TABLE_NAME = '{table.name}' AND TABLE_SCHEMA = '{table.db}' AND TABLE_CATALOG = '{table.catalog}')"""
-            if i < num_tables - 1:
-                query += " OR "
+            catalogs_to_tables.setdefault(table.args.get("catalog"), []).append(table)
+
+        results = []
+        for catalog, tables in catalogs_to_tables.items():
+            query = (
+                exp.select("LAST_ALTERED")
+                .from_(exp.table_("TABLES", db="INFORMATION_SCHEMA", catalog=catalog))
+                .where(
+                    exp.or_(
+                        *(
+                            exp.and_(
+                                exp.column("TABLE_NAME").eq(exp.Literal.string(table.name)),
+                                exp.column("TABLE_SCHEMA").eq(exp.Literal.string(table.db)),
+                            )
+                            for table in tables
+                        )
+                    )
+                )
+            )
+            results.extend(self.fetchall(query))
 
-        result = self.fetchall(query)
-        return [to_timestamp(row[0]) for row in result]
+        return [to_timestamp(row[0]) for row in results]
diff --git a/tests/core/engine_adapter/test_snowflake.py b/tests/core/engine_adapter/test_snowflake.py
index 05f0133ec8..89f19fc588 100644
--- a/tests/core/engine_adapter/test_snowflake.py
+++ b/tests/core/engine_adapter/test_snowflake.py
@@ -1,4 +1,5 @@
 import typing as t
+from datetime import datetime, timezone
 
 import pandas as pd  # noqa: TID253
 import pytest
@@ -14,6 +15,7 @@
 from sqlmesh.core.model import load_sql_based_model
 from sqlmesh.core.model.definition import SqlModel
 from sqlmesh.core.node import IntervalUnit
+from sqlmesh.utils.date import to_timestamp
 from sqlmesh.utils.errors import SQLMeshError
 from sqlmesh.utils import optional_import
 from tests.core.engine_adapter import to_sql_calls
@@ -73,6 +75,38 @@ def test_get_data_objects_lowercases_columns(
     assert data_object.clustering_key == "ID"
 
 
+def test_get_table_last_modified_ts_multiple_catalogs(
+    snowflake_mocked_engine_adapter: SnowflakeEngineAdapter,
+) -> None:
+    adapter = snowflake_mocked_engine_adapter
+    adapter.cursor.fetchall.side_effect = [
+        [
+            (datetime(2025, 1, 1, tzinfo=timezone.utc),),
+            (datetime(2025, 1, 2, tzinfo=timezone.utc),),
+        ],
+        [(datetime(2025, 1, 3, tzinfo=timezone.utc),)],
+    ]
+
+    result = adapter.get_table_last_modified_ts(
+        [
+            '"ANALYTICS"."STAGING"."ORDERS"',
+            '"RAW"."SHOPIFY"."ORDERS"',
+            '"ANALYTICS"."STAGING"."CUSTOMERS"',
+        ]
+    )
+
+    # INFORMATION_SCHEMA only covers the database it belongs to, so each database is queried separately
+    assert to_sql_calls(adapter) == [
+        """SELECT LAST_ALTERED FROM "ANALYTICS".INFORMATION_SCHEMA.TABLES WHERE (TABLE_NAME = 'ORDERS' AND TABLE_SCHEMA = 'STAGING') OR (TABLE_NAME = 'CUSTOMERS' AND TABLE_SCHEMA = 'STAGING')""",
+        """SELECT LAST_ALTERED FROM "RAW".INFORMATION_SCHEMA.TABLES WHERE TABLE_NAME = 'ORDERS' AND TABLE_SCHEMA = 'SHOPIFY'""",
+    ]
+    assert result == [
+        to_timestamp("2025-01-01"),
+        to_timestamp("2025-01-02"),
+        to_timestamp("2025-01-03"),
+    ]
+
+
 @pytest.mark.parametrize(
     "current_warehouse, current_warehouse_exp, configured_warehouse, configured_warehouse_exp, should_change",
     [
@@ -171,6 +205,29 @@ def test_session(
         assert to_sql_calls(adapter) == expected_exception_calls
 
 
+def test_get_table_last_modified_ts_quoted_and_unquoted_catalogs(
+    snowflake_mocked_engine_adapter: SnowflakeEngineAdapter,
+) -> None:
+    # unquoted raw resolves to the database RAW, quoted "raw" is a different database,
+    # so the two must be looked up in two different information schemas
+    adapter = snowflake_mocked_engine_adapter
+    adapter.cursor.fetchall.side_effect = [
+        [(datetime(2025, 1, 1, tzinfo=timezone.utc),)],
+        [(datetime(2025, 1, 2, tzinfo=timezone.utc),)],
+    ]
+
+    result = adapter.get_table_last_modified_ts(['"raw".shopify.orders', "raw.shopify.customers"])
+
+    assert result == [
+        to_timestamp(datetime(2025, 1, 1, tzinfo=timezone.utc)),
+        to_timestamp(datetime(2025, 1, 2, tzinfo=timezone.utc)),
+    ]
+    assert to_sql_calls(adapter) == [
+        """SELECT LAST_ALTERED FROM "raw".INFORMATION_SCHEMA.TABLES WHERE TABLE_NAME = 'orders' AND TABLE_SCHEMA = 'shopify'""",
+        """SELECT LAST_ALTERED FROM raw.INFORMATION_SCHEMA.TABLES WHERE TABLE_NAME = 'customers' AND TABLE_SCHEMA = 'shopify'""",
+    ]
+
+
 def test_comments(make_mocked_engine_adapter: t.Callable, mocker: MockerFixture):
     adapter = make_mocked_engine_adapter(SnowflakeEngineAdapter)